Congratulations, Nils, for winning this years poster prize at the European Nitrogen Fixation Conference, which was held in Naples (Italy) in September 2023! Here, we presented Nils‘ and our former PostDoc Chao’s unpublished work on a novel protein that drives membrane invaginations during symbiotic infections. Stay tuned for the manuscript that will be released (as always by us) as a pre-print on bioRxiv hopefully soon.
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Cell cycle stalling preceeds rhizobial infection
Our latest work cellular trajectories steering rhizobial infections is now out as a reviewed pre-print @eLife. Have a look. Great achievement of Morgane Batzenschlager from our lab! Congratulations Morgane and all co-authors involved.
Batzenschlager M, Lace B, Zhang N, Su C, Egli S, Krohn P, Salfeld J, Ditengou FA, Laux T and Ott T (2023)
Competence for transcellular infection in the root cortex involves a post-replicative, cell-cycle exit decision in Medicago truncatula
eLife (reviewed pre-print): https://doi.org/10.7554/eLife.88588.1
pre-print deposited at: bioRxiv; https://doi.org/10.1101/2023.03.28.534635 -
How infection threads pass the cell wall
We are happy to share a new pre-print from our lab, where we demonstrate the mechanism that allows infection threads to transcellularly pass from cell to cell during rhizobial colonisation of legume roots.
Any comments are always welcome:
Su C, Zhang G, Rodriguez-Franco M, Wietschorke J, Liang P, Yang W, Uhler L, Li X, Ott T (2022)
Transcellular progression of infection threads in Medicago truncatula roots is controlled by locally confined cell wall modifications
pre-printed deposited at: https://biorxiv.org/cgi/content/short/2022.07.07.499094v1 -
Collaborative work published in Plant Cell
Work led by the lab of Marco Trujillo is now accepted in Plant Cell. His lab shows that the Exocyst Subunit Exo70B2 is Linked to immunity and autophagy maintaining cellular homeostasis during enhanced secretory activity. We are grateful that we could contribute a bit to this nice project.
Congratulations to all authors!
Teh OK, Lee CW, Ditengou FA, Majovsky P, Klecker T, Furlan G, Zietz M, Hause G, Eschen-Lippold L, Hoehenwarter W, Lee J, Ott T, Trujillo M (2020)
Exocyst subunit Exo70B2 is linked to immune signalling and autophagy
accepted in Plant Cell
pre-print deposited at: bioRxiv, https://doi.org/10.1101/266171 -
New lab member
We are very happy to finally have Guofeng Zhang with us. He joins us from the Northwest Agriculture & Forestry University, China and will work on aspects of cell wall remodelling during symbiotic infections in legumes.
Welcome, Guofeng!
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Stay healthy and fight COVID19!
The whole team wishes everyone to stay healthy and thanks all support structures working for keeping our infrastructure running. #westayhome and #flattenthecurve.
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International conference on plant proteostasis
We are happy to see that the International Conference on Plant Proteostasis 2019 is hosted by Marco Trujillo from the Division of Cell Biology at the University of Freiburg in September 2019. Please find more about the exciting program here.
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Chao wins Poster Prize
Our PhD student Chao Su won the prize for the best poster at the iMMM2019 in Torino. Congratulations! Well done and deserved!
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Our work in CIBSS
Our work in frame of the newly funded excellence cluster ‘Centre for Integrative Biological Signalling Studies‘ (CIBSS) was just highlighted in the online magazine of the University of Freiburg. If you are interested, read the full article.
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PhD position available
Applications are invited for a Ph.D. position to join the Group of Marco Trujillo at the University of Freiburg.
Research in the Trujillo lab (www.trujillolab.com) focuses on understanding ubiquitin signalling and its roles in the regulation of immune responses and general protein homeostasis. Previous and ongoing research in the Lab has uncovered key roles of ubiquitination in the regulation intracellular vesicle transport and its interplay with signalling stemming from receptor kinases.
The Project
Newly synthesized membrane proteins are delivered to the plasma membrane in a highly specific and regulated manner through the secretory pathway. In this joint project with the laboratory of Thomas Ott (University of Freiburg; https://plantcellbiology.net), the successful candidate will work on elucidating regulatory mechanisms governing the secretory activity. The project encompasses a multidisciplinary approach combining biochemistry (structural biology, protein-protein & protein-lipid interaction analyses, enzyme activity assays, mass-spectrometry), and cell biology (CLSM, TIRF/VAEM).
This is an exciting opportunity for the applicant to join a multi-disciplinary research group within an international centre of excellence in sciences.
The ideal candidate
We are looking for a highly motivated individual with experience in protein biochemistry and cell biology. The successful candidate will possess a Master in Science (full award) in protein biochemistry or a related discipline. Can take initiative, function well in a team, and have a hands-on mentality, perseverance and critical mind-set. Proficiency in English language for both oral and written communication.
Reviewing of applications will start February 1st 2019 and continue until position is filled. The position is available immediately.
Additional Information
The position is funded by the DFG for three years. Salary will be according to the German Public Sector Agreement (E13, 65%) commensurate to qualifications and experience.
Please include for your application: Cover letter detailing your motivation and background for applying for the position, CV, copy of PhD degree, name and address of three referees.
For further information and details, please contact Marco Trujillo directly marco.trujillo@bio.uni-freiburg.de .
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EMBO course on Electron Microscopy
Registration is open for the EMBO course “Advanced methods of electron microscopy in cell biology” held between 10-20 June 2019 in České Budějovice, Czech Republic. We are also happy to announce that the head of our Electron Microscopy Facility, Marta Rodriguez-Franco, will be teaching there as well. Don’t miss to register and get inspired there. Check it out at
http://meetings.embo.org/event/19-advanced-em
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New confocal microscope funded!
We just received a letter from our funding agency (DFG) stating that our application for a new confocal microscope was fully accepted! So finally FLIM will be available in our imaging facility @MIAP_Freiburg. Thanks to all anonymous reviewers and DFG for the support.
