Thanks to the team of Véronique Germain and Sebastien Mongrand from the University of Bordeaux for letting us join their efforts to investigate the role of the partially plasma membrane-bound Calcium-dependent protein kinase 3 (CPK3) in viral infection. In their new work now published in eLife, they showed that CPK3 diffusion in the plasma membrane is reduced upon activation as well as upon viral infection and that such immobilization is depended on its substrate Remorin (REM1.2).
Congratulations to all authors!
Jolivet MD, Deroubaix AF, Boudsocq M, Abel NB, Rocher M, Robbe T, Wattelet-Boyer V, Huard J, Lefebvre D, Lu YJ, Day B, Saias G, Ahmed J, Cotelle V, Giovinazzo N, Gallois JL, Yamaji Y, German-Retana S, Gronnier J, Ott T, Mongrand S, Germain V (2025)
Interdependence of plasma membrane nanoscale dynamics of a kinase and its cognate substrate underlies Arabidopsis response to viral infection
eLife; 12:RP90309
pre-print deposited at: bioRxiv; https://doi.org/10.1101/2023.07.31.551174
