In this study we demonstrate that the remorin protein SYMREM1 can function as a membrane topology scaffold. The protein does not only induce distinct membrane structures but stabilizes those efficiently in the absence of a cell wall.
Congratulations to our first author Chao Su and all other co-authors who contributed with all their expertise to this work! That was fun working with all of you.
This work also demonstrates the strength of our truly interdisciplinary Cluster of Excellence CIBSS.
Su C, Rodriguez-Franco M, Lace B, Nebel N, Hernandez-Reyes C, Liang P, Schulze E, Mymrikov EV, Gross NM, Knerr J, Wang H, Siukstaite L, Keller J, Libourel C, Fischer AAM, Gabor KE, Mark E, Popp C, Hunte C, Weber W, Wendler P, Stanislas T, Delaux PM, Einsle O, Grosse R, Römer W, Ott T (2023)
Stabilization of membrane topologies by proteinaceous remorin scaffolds
Nature Communications; 14:323 (open access)
